TNFAIP8 Rabbit Polyclonal Antibody

CAT#: TA347583

Rabbit Polyclonal Anti-TFIP8 Antibody

Product Images

Western blot analysis on HuvEc cell lysate using TFIP8 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-TFIP8 Antibody: A synthesized peptide derived from human TFIP8
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 23 kDa
• Gene Name: TNF alpha induced protein 8
• Database Link:
  NP_055165
  Entrez Gene 106869 MouseEntrez Gene 25816 Human
  UniProt ID O95379
• Background: TNFAIP8 Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. Belongs to the TNFAIP8 family. Induced by nuclear factor-KB (NF-KB) and TNF. Induction by TNF depends upon activation of NF-KB.
• Synonyms: GG2-1; MDC-3.13; NDED; SCC-S2; SCCS2
• Note: TFIP8 Antibody detects endogenous levels of TFIP8

Reference Data

• Protein Families: Druggable Genome