ATG4B Rabbit Polyclonal Antibody

CAT#: TA347590

Rabbit Polyclonal Anti-ATG4B Antibody

Product Images

Western blot analysis on Jurkat cell lysate using ATG4B Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-ATG4B Antibody: A synthesized peptide derived from human ATG4B
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 44 kDa
• Gene Name: autophagy related 4B cysteine peptidase
• Database Link:
  NP_847896
  Entrez Gene 66615 MouseEntrez Gene 23192 Human
  UniProt ID Q9Y4P1
• Background: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Two transcript variants that encode different isoforms were identified through sequence analysis.
• Synonyms: APG4B; AUTL1
• Note: ATG4B Antibody detects endogenous levels of ATG4B

Reference Data

• Protein Families: Protease
• Protein Pathways: Regulation of autophagy