CD147 (BSG) Rabbit Polyclonal Antibody

CAT#: TA347592

Rabbit Polyclonal Anti-CD147 Antibody

Product Images

Western blot analysis on HuvEc cell lysate using CD147 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-CD147 Antibody: A synthesized peptide derived from human CD147
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 48,36 kDa
• Gene Name: basigin (Ok blood group)
• Database Link:
  NP_940993
  Entrez Gene 12215 MouseEntrez Gene 25246 RatEntrez Gene 682 Human
  UniProt ID P35613
• Background: BSG Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes. Enriched on the surface of tumor cells. Up-regulated in gliomas. Its expression levels correlate with malignant potential of the tumor.
• Synonyms: 5F7; CD147; EMMPRIN; OK; TCSF
• Note: CD147 Antibody detects endogenous levels of CD147

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane