CYP26A1 Rabbit Polyclonal Antibody

CAT#: TA347614

Rabbit Polyclonal Anti-Cytochrome P450 26A1 Antibody

Product Images

Western blot analysis on HepG2 cell lysate using Cytochrome P450 26A1 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Cytochrome P450 26A1 Antibody: A synthesized peptide derived from human Cytochrome P450 26A1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 56 kDa
• Gene Name: cytochrome P450 family 26 subfamily A member 1
• Database Link:
  NP_000774
  Entrez Gene 13082 MouseEntrez Gene 154985 RatEntrez Gene 1592 Human
  UniProt ID O43174
• Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported.
• Synonyms: CP26; CYP26; P450RAI; P450RAI1
• Note: Cytochrome P450 26A1 Antibody detects endogenous levels of Cytochrome P450 26A1

Reference Data

• Protein Families: Druggable Genome, P450, Transmembrane
• Protein Pathways: Retinol metabolism