BCAR3 Rabbit Polyclonal Antibody
Frequently bought together (3)
Recombinant protein of human breast cancer anti-estrogen resistance 3 (BCAR3)
USD 823.00
Transient overexpression lysate of breast cancer anti-estrogen resistance 3 (BCAR3)
USD 396.00
Other products for "BCAR3"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 1:500-1:2000 |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-BCAR3 Antibody: A synthesized peptide derived from human BCAR3 |
Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt |
Concentration | lot specific |
Purification | Immunogen affinity purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 92 kDa |
Gene Name | breast cancer anti-estrogen resistance 3 |
Database Link | |
Background | a ubiquitously expressed regulator of R-Ras activity that has been implicated in breast cancer. A GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1. Can accelerate the degradation of IRS-1, thus regulating signaling through the insulin receptor. When overexpressed, it confers anti-estrogen resistance in breast cancer cell lines. May also be regulated by cellular adhesion to extracellular matrix proteins. Up-regulated by interleukin-1-alpha and TNF-beta in thymus cortical reticular cell lines (mouse).Two alternatively spliced human isoforms have been described. |
Synonyms | NSP2; SH2D3B |
Note | BCAR3 Antibody detects endogenous levels of BCAR3 |
Reference Data | |
Protein Families | Druggable Genome |
Documents
Product Manuals |
FAQs |
SDS |
{0} Product Review(s)
0 Product Review(s)
Submit review
Be the first one to submit a review
Product Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.