MRC2 Rabbit Polyclonal Antibody

CAT#: TA347665

Rabbit Polyclonal Anti-MRC2 Antibody

Product Images

Western blot analysis on 293 cell lysate using MRC2 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-MRC2 Antibody: A synthesized peptide derived from human MRC2
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 167 kDa
• Gene Name: mannose receptor C type 2
• Database Link:
  NP_006030
  Entrez Gene 17534 MouseEntrez Gene 498011 RatEntrez Gene 9902 Human
  UniProt ID Q9UBG0
• Background: MRC2 May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover.
• Synonyms: CD280; CLEC13E; ENDO180; UPARAP
• Note: MRC2 Antibody detects endogenous levels of MRC2

Reference Data

• Protein Families: Druggable Genome, Transmembrane