GCKR Rabbit Polyclonal Antibody

CAT#: TA347669

Rabbit Polyclonal Anti-GCKR Antibody

Product Images

Western blot analysis on mouse heart cell lysate using GCKR Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-GCKR Antibody: A synthesized peptide derived from human GCKR
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 68 kDa
• Gene Name: glucokinase (hexokinase 4) regulator
• Database Link:
  NP_001477
  Entrez Gene 25658 RatEntrez Gene 231103 MouseEntrez Gene 2646 Human
  UniProt ID Q14397
• Background: This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
• Synonyms: FGQTL5; GKRP
• Note: GCKR Antibody detects endogenous levels of GCKR