COX17 Rabbit Polyclonal Antibody

CAT#: TA347704

Rabbit Polyclonal Anti-COX17 Antibody

Product Images

Western blot analysis on HeLa cell lysate using COX17 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-COX17 Antibody: A synthesized peptide derived from human COX17
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 7 kDa
• Gene Name: COX17 cytochrome c oxidase copper chaperone
• Database Link:
  NP_005685
  Entrez Gene 12856 MouseEntrez Gene 89786 RatEntrez Gene 10063 Human
  UniProt ID Q14061
• Background: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13.
• Synonyms: MGC104397; MGC117386
• Note: COX17 Antibody detects endogenous levels of COX17

Reference Data

• Protein Pathways: Metabolic pathways, Oxidative phosphorylation