DDIT3 Rabbit Polyclonal Antibody

CAT#: TA347707

Rabbit Polyclonal Anti-GADD153 Antibody

Product Images

Western blot analysis on Jurkat cell lysate using GADD153 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-GADD153 Antibody: A synthesized peptide derived from human GADD153
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 26 kDa
• Gene Name: DNA damage inducible transcript 3
• Database Link:
  NP_004074
  Entrez Gene 13198 MouseEntrez Gene 29467 RatEntrez Gene 1649 Human
  UniProt ID P35638
• Background: CHOP a transcriptional-regulatory protein of the bZIP family. Inhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA. May play an important role in melanoma progression. CK2-mediated phosphorylation inhibits its transcriptional activity. Up-regulates IL-6 transcription by trapping negative regulating NF-IL6 isoform.
• Synonyms: CEBPZ; CHOP; CHOP-10; CHOP10; GADD153
• Note: GADD153 Antibody detects endogenous levels of GADD153

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: MAPK signaling pathway