SURF1 Rabbit Polyclonal Antibody

CAT#: TA347735

Rabbit Polyclonal Anti-SURF1 Antibody

Product Images

Western blot analysis on Jurkat cell lysate using SURF1 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-SURF1 Antibody: A synthesized peptide derived from human SURF1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 30 kDa
• Gene Name: surfeit 1
• Database Link:
  NP_003163
  Entrez Gene 20930 MouseEntrez Gene 64463 RatEntrez Gene 6834 Human
  UniProt ID Q15526
• Background: This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.
• Synonyms: CMT4K
• Note: SURF1 Antibody detects endogenous levels of SURF1

Reference Data

• Protein Families: Druggable Genome