KSR2 Rabbit Polyclonal Antibody

CAT#: TA347742

Rabbit Polyclonal Anti-KSR2 Antibody

Product Images

Western blot analysis on 293 cell lysate using KSR2 Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-KSR2 Antibody: A synthesized peptide derived from human KSR2
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 108 kDa
• Gene Name: kinase suppressor of ras 2
• Database Link:
  NP_775869
  Entrez Gene 333050 MouseEntrez Gene 283455 Human
  UniProt ID Q6VAB6
• Background: KSR2 Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Interacts with MAP2K1, MAP3K8, MAPK, RAS and RAF. 2 isoforms of the human protein are produced by alternative splicing.
• Synonyms: FLJ25965
• Note: KSR2 Antibody detects endogenous levels of KSR2

Reference Data

• Protein Families: Druggable Genome, Protein Kinase