PRAK (MAPKAPK5) Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 1:500-1:2000 |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The immunogen for anti-MAPKAPK5 Antibody: A synthesized peptide derived from human MAPKAPK5 |
Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt |
Concentration | lot specific |
Purification | Immunogen affinity purified |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 60 kDa |
Gene Name | mitogen-activated protein kinase-activated protein kinase 5 |
Database Link | |
Background | The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Synonyms | MAPKAP-K5; MK-5; MK5; PRAK |
Note | MAPKAPK5 Antibody detects endogenous levels of MAPKAPK5 |
Reference Data | |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | MAPK signaling pathway |
Documents
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