FLT4 Rabbit Polyclonal Antibody

CAT#: TA347855

Rabbit Polyclonal Anti-VEGFR3 Antibody

Product Images

Western blot analysis of extracts from HUVEC cells using VEGFR-3 Antibody (right) and the same antibody preincubated with blocking peptide

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:1000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-VEGFR3 Antibody: Peptide sequence around aa.1279~1283 (L-A-S-E-E) derived from Human VEGFR-3.
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 160kd
• Gene Name: fms related tyrosine kinase 4
• Database Link:
  NP_891555
  Entrez Gene 14257 MouseEntrez Gene 2324 Human
  UniProt ID P35916
• Background: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC
• Synonyms: FLT-4; FLT41; LMPH1A; PCL; VEGFR-3; VEGFR3
• Note: The antibody detects endogenous level of total VEGFR-3 protein.

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Focal adhesion