MADH7 (SMAD7) Rabbit Polyclonal Antibody

CAT#: TA347891

Rabbit Polyclonal Anti-Smad7 Antibody

Product Images

Western blot analysis of Smad7 expression in Human Kidney lysate

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1/500
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Smad7 Antibody: A synthesized peptide
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 50KD
• Gene Name: SMAD family member 7
• Database Link:
  NP_005895
  Entrez Gene 17131 MouseEntrez Gene 81516 RatEntrez Gene 4092 Human
  UniProt ID O15105
• Background: Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex.
• Synonyms: CRCS3; MADH7; MADH8
• Note: Smad7 Antibody detects endogenous levels of total Smad7

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: TGF-beta signaling pathway