Bcl2 Binding component 3 (BBC3) Rabbit Polyclonal Antibody

CAT#: TA347903

Rabbit Polyclonal Anti-BBC3(PUMA) Antibody

Product Images

Western blot analysis of BBC3 (PUMA) expression in 293 cells

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-BBC3(PUMA) Antibody: A synthesized peptide derived from human BBC3(PUMA)
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 20 kDa
• Gene Name: BCL2 binding component 3
• Database Link:
  NP_055232
  Entrez Gene 170770 MouseEntrez Gene 317673 RatEntrez Gene 27113 Human
  UniProt ID Q96PG8
• Background: Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis
• Synonyms: JFY-1; JFY1; PUMA
• Note: BBC3(PUMA) Antibody detects endogenous levels of total BBC3(PUMA)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Huntington's disease, p53 signaling pathway