Angiotensin Converting Enzyme 1 (ACE) Rabbit Polyclonal Antibody

CAT#: TA347909

Rabbit Polyclonal Anti-ACE1 Antibody

Product Images

Western blot analysis of ACE1 expression in mouse kidney

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-ACE1 Antibody: A synthesized peptide derived from human ACE1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 149 kDa
• Gene Name: angiotensin I converting enzyme
• Database Link:
  NP_001171528
  Entrez Gene 11421 MouseEntrez Gene 24310 RatEntrez Gene 1636 Human
  UniProt ID P12821
• Background: Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.
• Synonyms: ACE1; CD143; DCP; DCP1
• Note: ACE1 Antibody detects endogenous levels of total ACE1

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Protease, Secreted Protein, Transmembrane
• Protein Pathways: Hypertrophic cardiomyopathy (HCM), Renin-angiotensin system