Eph receptor A2 (EPHA2) Rabbit Polyclonal Antibody

CAT#: TA347931

Rabbit Polyclonal Anti-EPHA2 Antibody

Product Images

Western blot analysis of EPHA2 expression in Jurkat cells

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-EPHA2 Antibody: A synthesized peptide derived from human EPHA2
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 108 kDa
• Gene Name: EPH receptor A2
• Database Link:
  NP_004422
  Entrez Gene 13836 MouseEntrez Gene 1969 Human
  UniProt ID P29317
• Background: Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 and -A5. Plays an important role in angiogenesis and tumor neovascularization. The recruitement of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). Induces apoptosis in a p53/TP53-independent, caspase-8-dependent manner.
• Synonyms: ARCC2; CTPA; CTPP1; CTRCT6; ECK
• Note: EPHA2 Antibody detects endogenous levels of total EPHA2

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Axon guidance