Caspase 9 (CASP9) Rabbit Polyclonal Antibody

CAT#: TA347933

Rabbit Polyclonal Anti-Caspase 9 (Cleaved-Asp353) Antibody

Product Images

Western blot analysis of Caspase 9 (Cleaved-Asp353) expression in NIH/3T3 cells treated with etoposide

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Caspase 9 (Cleaved-Asp353) Antibody: A synthesized peptide derived from human Caspase 9 (Cleaved-Asp353)
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 10 kDa
• Gene Name: caspase 9
• Database Link:
  NP_001220
  Entrez Gene 12371 MouseEntrez Gene 58918 RatEntrez Gene 842 Human
  UniProt ID P55211
• Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
• Synonyms: APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56
• Note: Caspase 9 (Cleaved-Asp353) Antibody detects endogenous levels of total Caspase 9 (Cleaved-Asp353)

Reference Data

• Protein Families: Druggable Genome, Protease, Stem cell - Pluripotency
• Protein Pathways: Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Endometrial cancer, Huntington's disease, Non-small cell lung cancer, p53 signaling pathway, Pancreatic cancer, Parkinson's disease, Pathways in cancer, Prostate cancer, Small cell lung cancer, VEGF signaling pathway, Viral myocarditis