Metabotropic Glutamate Receptor 5 (GRM5) Rabbit Polyclonal Antibody

CAT#: TA347934

Rabbit Polyclonal Anti-GRM5 Antibody

Product Images

Western blot analysis of GRM5 expression in HT-29 cells

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:1000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-GRM5 Antibody: A synthesized peptide derived from internal of human GRM5.
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 120kd
• Gene Name: glutamate metabotropic receptor 5
• Database Link:
  NP_001137303
  Entrez Gene 24418 RatEntrez Gene 108071 MouseEntrez Gene 2915 Human
  UniProt ID P41594
• Background: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current
• Synonyms: GPRC1E; mGlu5; MGLUR5; PPP1R86
• Note: GRM5 antibody detects endogenous levels of total GRM5 protein.

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Gap junction, Huntington's disease, Long-term depression, Long-term potentiation, Neuroactive ligand-receptor interaction