NOTCH2 Rabbit Polyclonal Antibody

CAT#: TA347941

Rabbit Polyclonal Anti-NOTCH2 (Cleaved-Ala1734) Antibody

Product Images

Western blot analysis of NOTCH2 (Cleaved-Ala1734) expression in Jurkat cells, treated with etoposide

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-NOTCH2 (Cleaved-Ala1734) Antibody: A synthesized peptide derived from human NOTCH2 (Cleaved-Ala1734)
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 110 kDa
• Gene Name: notch 2
• Database Link:
  NP_001186930
  Entrez Gene 18129 MouseEntrez Gene 29492 RatEntrez Gene 4853 Human
  UniProt ID Q04721
• Background: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus.
• Synonyms: AGS2; HJCYS; hN2
• Note: NOTCH2 (Cleaved-Ala1734) Antibody detects endogenous levels of total NOTCH2 (Cleaved-Ala1734)

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Dorso-ventral axis formation, Notch signaling pathway