Myosin light chain kinase (MYLK) Rabbit Polyclonal Antibody

CAT#: TA347970

Rabbit Polyclonal Anti-MYLK Antibody

Product Images

Western blot analysis of MYLK expression in HepG2 cells

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-MYLK Antibody: A synthesized peptide derived from human MYLK
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 211 kDa.
• Gene Name: myosin light chain kinase
• Database Link:
  NP_444259
  Entrez Gene 107589 MouseEntrez Gene 288057 RatEntrez Gene 4638 Human
  UniProt ID Q15746
• Background: Calcium/calmodulin-dependent enzyme implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activty (By similarity). Implicated in the regulation of endothelial as well as vascular permeability.
• Synonyms: AAT7; KRP; MLCK; MLCK1; MLCK108; MLCK210; MSTP083; MYLK1; smMLCK
• Note: MYLK Antibody detects endogenous levels of total MYLK

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Calcium signaling pathway, Focal adhesion, Regulation of actin cytoskeleton, Vascular smooth muscle contraction