MRE11 Rabbit Polyclonal Antibody

CAT#: TA347972

Rabbit Polyclonal Anti-MRE11A Antibody

Product Images

Western blot analysis of MRE11A expression in LOVO cells

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-MRE11A Antibody: A synthesized peptide derived from human MRE11A
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 80 kDa
• Gene Name: MRE11 homolog A, double strand break repair nuclease
• Database Link:
  NP_005582
  Entrez Gene 17535 MouseEntrez Gene 64046 RatEntrez Gene 4361 Human
  UniProt ID P49959
• Background: Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity
• Synonyms: ATLD; HNGS1; MRE11; MRE11B
• Note: MRE11A Antibody detects endogenous levels of total MRE11A

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Homologous recombination, Non-homologous end-joining