E3 SUMO protein ligase PIAS4 (PIAS4) Rabbit Polyclonal Antibody

CAT#: TA347977

Rabbit Polyclonal Anti-PIAS4 Antibody

Product Images

Western blot analysis of PIAS4 expression in Jurkat cell extract

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-PIAS4 Antibody: A synthesized peptide derived from human PIAS4
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 57 kDa
• Gene Name: protein inhibitor of activated STAT 4
• Database Link:
  NP_056981
  Entrez Gene 59004 MouseEntrez Gene 51588 Human
  UniProt ID Q8N2W9
• Background: Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway, the Wnt pathway and the steroid hormone signaling pathway.
• Synonyms: PIAS-gamma; Piasg; PIASY; ZMIZ6
• Note: PIAS4 Antibody detects endogenous levels of total PIAS4

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: Jak-STAT signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis