DNA PKcs (PRKDC) Rabbit Polyclonal Antibody

CAT#: TA347982

Rabbit Polyclonal Anti-DNA PK Antibody

Product Images

Western blot analysis of DNA PK expression in K562 cells

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-DNA PK Antibody: A synthesized peptide derived from human DNA PK
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 469 kDa
• Gene Name: protein kinase, DNA-activated, catalytic polypeptide
• Database Link:
  NP_001075109
  Entrez Gene 19090 MouseEntrez Gene 5591 Human
  UniProt ID P78527
• Background: Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties.
• Synonyms: DNA-PKcs; DNAPK; DNPK1; HYRC; HYRC1; IMD26; p350; XRCC7
• Note: DNA PK Antibody detects endogenous levels of total DNA PK

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Cell cycle, Non-homologous end-joining