BMPR2 Rabbit Polyclonal Antibody

CAT#: TA348001

Rabbit Polyclonal Anti-BMPR2 Antibody

Product Images

Western blot analysis of BMPR2 expression in H1299 whole cell lysate

Specifications

Product Data

• Applications: WB
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-BMPR2 Antibody: A synthesized peptide derived from human BMPR2
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 115 kDa
• Gene Name: bone morphogenetic protein receptor type 2
• Database Link:
  NP_001195
  Entrez Gene 12168 MouseEntrez Gene 140590 RatEntrez Gene 659 Human
  UniProt ID Q13873
• Background: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators.
• Synonyms: BMPR-II; BMPR3; BMR2; BRK-3; POVD1; PPH1; T-ALK
• Note: BMPR2 Antibody detects endogenous levels of total BMPR2

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, TGF-beta signaling pathway