53BP1 (TP53BP1) Rabbit Polyclonal Antibody

CAT#: TA348022

Rabbit Polyclonal Anti-53BP1 Antibody

Product Images

Western blot analysis of 53BP1 expression in HUVEC cells

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-53BP1 Antibody: A synthesized peptide derived from human 53BP1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 214 kDa
• Gene Name: tumor protein p53 binding protein 1
• Database Link:
  NP_005648
  Entrez Gene 7158 Human
  UniProt ID Q12888
• Background: Binds to the central domain of p53/TP53. May form homooligomers. Interacts with DCLRE1C. Interacts with histone H2AFX and this requires phosphorylation of H2AFX on 'Ser-139'. Interacts with histone H4 that has been dimethylated at 'Lys-20' (H4K20me2). Has low affinity for histone H4 containing monomethylated 'Lys-20' (H4K20me1).
• Synonyms: 53BP1; p202
• Note: 53BP1 Antibody detects endogenous levels of total 53BP1

Reference Data

• Protein Families: Druggable Genome, Transcription Factors