PYK2 (PTK2B) Rabbit Polyclonal Antibody

CAT#: TA348419

Rabbit Polyclonal Anti-Phospho-PYK2(Tyr580) Antibody


USD 380.00

4 Weeks*

Size
    • 100 ug

Product Images

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Specifications

Product Data
Applications WB
Recommended Dilution WB: 1:500-1:2000
Reactivities Human, Mouse, Rat
Modifications Phospho-specific
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen The immunogen for anti-Phospho-PYK2(Tyr580) Antibody: A synthesized peptide derived from human PYK2 around the phosphorylation site of Tyrosine 580
Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
Concentration lot specific
Purification Immunogen affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 135 kDa
Gene Name protein tyrosine kinase 2 beta
Background Pyk2 a nonreceptor tyrosine kinase of the Fak family. Predominantly expressed in the cells derived from hematopoietic lineages and in the central nervous system. Pyk2 is one of the signaling mediators for G-protein-coupled receptors. Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. Interacts with the SH2 domain of Grb2.
Synonyms CADTK; CAKB; FADK2; FAK2; PKB; PTK; PYK2; RAFTK
Note Phospho-PYK2(Tyr580) Antibody detects endogenous levels of PYK2 only when phosphorylated at Tyrosine 580
Reference Data
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Calcium signaling pathway, Chemokine signaling pathway, GnRH signaling pathway, Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.