Eph receptor A2 (EPHA2) Rabbit Polyclonal Antibody

CAT#: TA348421

Rabbit Polyclonal Anti-Phospho-EPHA2/3(Tyr588/596) Antibody

Product Images

Western blot analysis on HepG2 cell lysate using Phospho-EPHA2/3 (Tyr588/596) Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Phospho-EPHA2/3(Tyr588/596) Antibody: A synthesized peptide derived from human EPHA2/3 around the phosphorylation site of Tyrosine 588 and 596
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 130 kDa
• Gene Name: EPH receptor A2
• Database Link:
  NP_004422
  Entrez Gene 13836 MouseEntrez Gene 366492 RatEntrez Gene 1969 Human
  UniProt ID P29317
• Background: EphA2 a receptor tyrosine kinase. Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 AND -A5. The Eph receptor tyrosine kinase family, the largest in the tyrosine kinase group, has fourteen members. They bind membrane-anchored ligands, ephrins, at sites of cell-cell contact, regulating the repulsion and adhesion of cells that underlie the establishment, maintenance, and remodeling of patterns of cellular organization. Eph signals are particularly important in regulating cell adhesion and cell migration during development, axon guidance, homeostasis and disease.
• Synonyms: ARCC2; CTPA; CTPP1; CTRCT6; ECK
• Note: Phospho-EPHA2/3(Tyr588/596) Antibody detects endogenous levels of EPHA2 and 3 only when phosphorylated at Tyrosine 588 and 596

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Axon guidance