EMA (MUC1) Rabbit Polyclonal Antibody

CAT#: TA348427

Rabbit Polyclonal Anti-Phospho-CD227/MUC1(Tyr1229) Antibody

Product Images

Western blot analysis on HepG2 cell lysate using Phospho-CD227/MUC1 (Tyr1229) Antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Phospho-CD227/MUC1(Tyr1229) Antibody: A synthesized peptide derived from human CD227/MUC1 around the phosphorylation site of Tyrosine 1229
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 170 kDa
• Gene Name: mucin 1, cell surface associated
• Database Link:
  NP_002447
  Entrez Gene 4582 Human
  UniProt ID P15941
• Background: This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. This protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. The protein serves a protective function, binding to pathogens, as well as functioning in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Synonyms: ADMCKD; ADMCKD1; CA 15-3; CD227; EMA; H23AG; KL-6; MAM6; MCD; MCKD; MCKD1; MUC-1; SEC
• Note: Phospho-CD227/MUC1(Tyr1229) Antibody detects endogenous levels of CD227 and MUC1 only when phosphorylated at Tyrosine 1229

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane