EPS15 Rabbit Polyclonal Antibody

CAT#: TA348437

Rabbit Polyclonal Anti-Phospho-EPS15(Tyr849) Antibody

Product Images

Western blot analysis on HepG2 cell lysate using Phospho-EPS15 (Tyr849) Antibody

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Phospho-EPS15(Tyr849) Antibody: A synthesized peptide derived from human EPS15 around the phosphorylation site of Tyrosine 849
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 98 kDa
• Gene Name: epidermal growth factor receptor pathway substrate 15
• Database Link:
  NP_001972
  Entrez Gene 13858 MouseEntrez Gene 313474 RatEntrez Gene 2060 Human
  UniProt ID P42566
• Background: This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
• Synonyms: AF-1P; AF1P; MLLT5
• Note: Phospho-EPS15(Tyr849) Antibody detects endogenous levels of EPS15 only when phosphorylated at Tyrosine 849

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis