Nucleophosmin (NPM1) Rabbit Polyclonal Antibody

CAT#: TA348560

Rabbit Polyclonal Anti-Phospho-NPM (Thr199) Antibody

Product Images

Western blot analysis of NPM phosphorylation expression in Jurkat whole cell lysates, the lane on the left is treated with the antigen-specific peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-Phospho-NPM (Thr199) Antibody: A synthesized peptide derived from human NPM around the phosphorylation site of Threonine 199
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt
• Concentration: lot specific
• Purification: Immunogen affinity purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 32 38 kDa
• Gene Name: nucleophosmin (nucleolar phosphoprotein B23, numatrin)
• Database Link:
  NP_954654
  Entrez Gene 18148 MouseEntrez Gene 25498 RatEntrez Gene 4869 Human
  UniProt ID P06748
• Background: a nucleolar protein associated with nucleolar ribonucleoprotein structures and that binds single-stranded nucleic acids. Is a major component of template activating factor (TAF)-III. It plays a role in controlling centrosome duplication, and may function in the assembly and/or transport of the ribosome. Two alternatively spliced isoforms have been described.
• Synonyms: B23; NPM
• Note: Phospho-NPM (Thr199) Antibody detects endogenous levels of NPM only when phosphorylated at Threonine 199

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency, Transcription Factors