Caspase 1 (CASP1) Rabbit Polyclonal Antibody

CAT#: TA348921

Rabbit Polyclonal Anti-Caspase 1 (Phospho-Ser376) Antibody


USD 380.00

4 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Applications WB
Recommended Dilution WB: 1:500-1:2000
Reactivities Human, Mouse
Modifications Phospho-specific
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen The immunogen for anti-Caspase 1 (Phospho-Ser376) Antibody: A synthesized peptide derived from human Caspase 1 (Phospho-Ser376)
Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 ?.Stable for 12 months from date of receipt
Concentration lot specific
Purification Immunogen affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 27 kDa
Gene Name caspase 1
Background Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
Synonyms ICE; IL1BC; P45
Note Caspase 1 (Phospho-Ser376) Antibody detects endogenous levels of total Caspase 1 (Phospho-Ser376)
Reference Data
Protein Families Druggable Genome, Protease
Protein Pathways Amyotrophic lateral sclerosis (ALS), Cytosolic DNA-sensing pathway, NOD-like receptor signaling pathway

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.