PON2 Goat Polyclonal Antibody

CAT#: TA348946

Goat Polyclonal Anti-PON2 Antibody


USD 429.00

5 Days*

Size
    • 100 ug

Product Images

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Specifications

Product Data
Applications IHC
Recommended Dilution IHC: 2-4 ug/ml
Reactivities Human (Expected from sequence similarity: Mouse, Rat, Dog, Pig, Cow)
Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen The immunogen for Anti-PON2 Antibody: Peptide with sequence C-ERLLALRNRLKAS, from the internal region of the protein sequence according to NP_000296.2; NP_001018171.1.
Formulation Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Concentration lot specific
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name paraoxonase 2
Background This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Synonyms A-esterase 2; aromatic esterase 2; arylesterase 2; paraoxonase 2; paraoxonase nirs; serum aryldialkylphosphatase 2; serum paraoxonase
Note This antibody is expected to recognize isoforms 1 and 2 (NP_000296.2; NP_001018171.1).
Reference Data
Protein Families Druggable Genome
Protein Pathways Metabolic pathways

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.