OLIG2 Rabbit Polyclonal Antibody

CAT#: TA349016

Rabbit Polyclonal Anti-NOD1 Antibody

Product Images

Western blot analysis of NOD1 in EL4 cell lysate with NOD1 antibody at 1 ug/mL.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: NOD1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy end of human NOD1.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: NOD1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: oligodendrocyte lineage transcription factor 2
• Database Link:
  NP_005797
  Entrez Gene 50913 MouseEntrez Gene 304103 RatEntrez Gene 10215 Human
  UniProt ID Q13516
• Background: NOD1 Antibody: NOD1 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD1 contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and ten tandem leucine-rich repeats (LRRs) in its C-terminus. The CARD is involved in apoptotic signaling, and NOD1 activates caspase-9 and NF-κB. LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid.
• Synonyms: BHLHB1; bHLHe19; OLIGO2; PRKCBP2; RACK17

Reference Data

• Protein Families: Druggable Genome, Transcription Factors