ANGPTL3 Rabbit Polyclonal Antibody

CAT#: TA349022

Rabbit Polyclonal Anti-LAMTOR2 Antibody

Product Images

Western blot analysis of LAMTOR2 in HepG2 cell lysate with LAMTOR2 antibody at 1 ug/mL.

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  Immunohistochemistry of LAMTOR2 in human spleen tissue with LAMTOR2 antibody at 5 ug/mL.

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  Immunofluorescence of LAMTOR2 in human spleen tissue with LAMTOR2 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: LAMTOR2 antibody was raised against an 18 amino acid peptide near the center of human LAMTOR2.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: LAMTOR2 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 14 kDa; Observed: 16 kDa
• Gene Name: angiopoietin like 3
• Database Link:
  NP_055310
  Entrez Gene 30924 MouseEntrez Gene 502970 RatEntrez Gene 27329 Human
  UniProt ID Q9Y5C1
• Background: The late endosomal/lysosomal adaptor MAPK and MTOR activator 2 (LAMTOR2) protein belongs to the LAMTOR family of proteins, and together with LAMTOR3 and the MAPK1 and ERK kinase 1 (MEK1) localizes to late endosomes where it is required for the efficient activation of ERK signaling (1,2). This complex is involved in the regulation of late endosomal traffic and cellular proliferation (3) and plays a role in cellular host defense against Salmonella infection (4).
• Synonyms: ANG-5; ANGPT5; ANL3; FHBL2

Reference Data

• Protein Families: Druggable Genome, Secreted Protein