USP25 Rabbit Polyclonal Antibody

CAT#: TA349039

Rabbit Polyclonal Anti-UBIAD1 Antibody

Product Images

Western blot analysis of UBIAD1 in mouse liver tissue lysate with UBIAD1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

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  Immunohistochemistry of UBIAD1 in mouse liver tissue with UBIAD1 antibody at 5 ug/mL.

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  Immunofluorescence of UBIAD1 in mouse liver tissue with UBIAD1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: UBIAD1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human UBIAD1.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: UBIAD1 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 37 kDa; Observed: 45 kDa
• Gene Name: ubiquitin specific peptidase 25
• Database Link:
  NP_037528
  Entrez Gene 30940 MouseEntrez Gene 29761 Human
  UniProt ID Q9UHP3
• Background: The UbiA prenyltransferase domain containing 1 (UBIAD1) protein , also known as TERE1, was initially identified as a down-regulated gene in transitional cell carcinoma of the bladder (1). Recently it has been shown to bind the cholesterol carrier APOE and modulate cellular cholesterol levels (2). Mutations in the UBIAD1 gene can cause Schnyder crystalline corneal dystrophy, an autosomal dominant disease characterized by progressive opacification of the cornea resulting from the local accumulation of lipids (3).
• Synonyms: USP21

Reference Data

• Protein Families: Protease