IFIT1 Rabbit Polyclonal Antibody

CAT#: TA349041

Rabbit Polyclonal Anti-IFIT1 Antibody

Product Images

Western blot analysis of IFIT1 in rat small intestine tissue lysate with IFIT1 antibody at 1 ug/mL.

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  Immunohistochemistry of IFIT1 in human small intestine tissue with IFIT1 antibody at 5 ug/mL.

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  Immunofluorescence of IFIT1 in human small intestine tissue with IFIT1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: IFIT1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IFIT1.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: IFIT1 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 53 kDa; Observed: 53 kDa
• Gene Name: interferon induced protein with tetratricopeptide repeats 1
• Database Link:
  NP_001539
  Entrez Gene 15957 MouseEntrez Gene 56824 RatEntrez Gene 3434 Human
  UniProt ID P09914
• Background: The interferon-induced protein with tetratricopeptide repeats 1 (IFIT1) protein is a member of a family of tetratricopeptide repeat-containing proteins whose transcription is upregulated by interferons, virus infection, and molecular patterns such as dsRNA or lipopolysaccharides (1,2). These proteins have been suggested to induce anti-viral cellular activities in response to infection (2). Together with the interferon-induced transmembrane protein 1 (IFITM1), IFIT1 inhibits the replication of the Hepatitis C virus, suggesting that it may be useful in the development of therapeutic treatments (3).
• Synonyms: C56; G10P1; IFI-56; IFI-56K; IFI56; IFIT-1; IFNAI1; ISG56; P56; RNM561