ULBP4 (RAET1E) Rabbit Polyclonal Antibody

CAT#: TA349044

Rabbit Polyclonal Anti-DCNP1 Antibody

Product Images

Western blot analysis of DCNP1 in mouse skeletal muscle tissue lysate with DCNP1 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunohistochemistry of DCNP1 in mouse skeletal muscle tissue with DCNP1 antibody at 5 ug/mL.

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  Immunofluorescence of DCNP1 in mouse skeletal muscle tissue with DCNP1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: DCNP1 antibody was raised against an 18 amino acid peptide near the amino terminus of human DCNP1.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: DCNP1 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 27 kDa; Observed: 24 kDa
• Gene Name: retinoic acid early transcript 1E
• Database Link:
  NP_631904
  Entrez Gene 379043 MouseEntrez Gene 135250 Human
  UniProt ID Q8TD07
• Background: The DCNP1 (dendritic cell nuclear protein 1) gene is specifically expressed in dendritic cells, potent antigen-presenting cells involved in activating naive T cells to initiate antigen-specific immune response (1). It is localized mainly in the perinucleus. One of the alleles (A/T) of this gene causes premature translation termination at aa 117 and has been associated with an increased prevalence of major depression in humans (2,3). DCNP1 may play a role in the pathogenesis of depressive disorders by enhancing corticotropin-releasing hormone expression in the hypothalamic paraventricular nucleus (4).
• Synonyms: bA350J20.7; LETAL; N2DL-4; NKG2DL4; RAET1E2; RL-4; ULBP4

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Natural killer cell mediated cytotoxicity