INPP4B Rabbit Polyclonal Antibody

CAT#: TA349049

Rabbit Polyclonal Anti-PROM1 Antibody

Product Images

Western blot analysis of PROM1 in Jurkat cell lysate with PROM1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

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  Immunocytochemistry of PROM1 in Jurkat cells with PROM1 antibody at 2.5 ug/mL.

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  Immunofluorescence of PROM1 in Jurkat cells with PROM1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 2.5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: PROM1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human PROM1.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: PROM1 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 95 kDa; Observed: 97 kDa
• Gene Name: inositol polyphosphate-4-phosphatase type II B
• Database Link:
  NP_003857
  Entrez Gene 116699 RatEntrez Gene 234515 MouseEntrez Gene 8821 Human
  UniProt ID O15327
• Background: PROM1 is a pentaspan transmembrane glycoprotein that localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation (1). Mutations in this gene have been shown to result in retinitis pigmentosa (2). Expression of this gene is also associated with several types of cancer (3).
• Synonyms: MGC132014

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system