PPM1D Rabbit Polyclonal Antibody

CAT#: TA349066

Rabbit Polyclonal Anti-NDST2 Antibody

Product Images

Western blot analysis of NDST2 in A-20 cell lysate with NDST2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

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  Immunofluorescence of NDST2 in Daudi cells with NDST2 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: NDST2 antibody was raised against a 16 amino acid peptide near the amino terminus of human NDST2
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: NDST2 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 97 kDa; Observed: 101 kDa
• Gene Name: protein phosphatase, Mg2+/Mn2+ dependent 1D
• Database Link:
  NP_003611
  Entrez Gene 53892 MouseEntrez Gene 287585 RatEntrez Gene 8493 Human
  UniProt ID O15297
• Background: The N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 (NDST2) protein, also known as N-heparan sulfate sulfotransferase 2, and the highly related protein NDST1 have key roles in the sulfation of heparan sulfate proteoglycans, molecules that are present of cell surfaces and the extracellular matrix (1,2). NDST1 and NDST2 are dispensable for mesodermal differentiation into osteoblasts but necessary for induction of adipocytes and neural cells (3).
• Synonyms: PP2C-DELTA; WIP1

Reference Data

• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: p53 signaling pathway