SOX17 Rabbit Polyclonal Antibody

CAT#: TA349078

Rabbit Polyclonal Anti-SOX17 Antibody

Product Images

Western blot analysis of SOX17 in HepG2 cell lysate with SOX17 antibody at (A) 0.5 and (B) 1 ug/mL.

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  Immunofluorescence of SOX17 in mouse liver tissue with SOX17 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 0.5 - 1 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SOX17 antibody was raised against a 16 amino acid peptide near the center of human SOX17.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: SOX17 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 46 kDa; Observed: 42 kDa
• Gene Name: SRY-box 17
• Database Link:
  NP_071899
  Entrez Gene 20671 MouseEntrez Gene 312936 RatEntrez Gene 64321 Human
  UniProt ID Q9H6I2
• Background: SOX17 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate (1,2). SOX17 is part of the SoxF subgroup which plays an important role in the differentiation of different cell types, including visceral and definitive endoderm and hematopoietic cell types (3,4). SOX17 is also essential for acquisition and maintenance of arterial identity (5).
• Synonyms: PRAJA1; RNF70

Reference Data

• Protein Families: Transcription Factors
• Protein Pathways: Wnt signaling pathway