Myosin heavy chain 3 (MYH3) Rabbit Polyclonal Antibody

CAT#: TA349138

Rabbit Polyclonal Anti-MYH3 Antibody

Product Images

Western blot analysis of MYH3 in Jurkat cell lysate with MYH3 antibody at 1 ug/mL.

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  Immunohistochemistry of MYH3 in mouse skeletal muscle tissue with MYH3 antibody at 5 ug/mL.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: MYH3 antibody was raised against a 19 amino acid peptide near the amino terminus of human MYH3.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: MYH3 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 213 kDa; Observed: 240 kDa
• Gene Name: myosin, heavy chain 3, skeletal muscle, embryonic
• Database Link:
  NP_002461
  Entrez Gene 4621 Human
  UniProt ID P11055
• Background: Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells (1). MYH3 (myosin, heavy chain, skeletal muscle, embryonic) plays a significant role in skeletal muscle development (2) and is also essential for the proper morphology and function of the developing heart (3). Mutations in this gene have been associated with Freeman-Sheldon syndrome and Sheldon-Hall syndrome (4).
• Synonyms: Myosin heavy chain 3, Myosin-3, Myosin heavy chain skeletal muscle embryonic, HEMHC, MYHC-EMB, MYHSE1, SMHCE