PI 3 Kinase Class 3 (PIK3C3) Rabbit Polyclonal Antibody

CAT#: TA349141

Rabbit Polyclonal Anti-PRRX1 Antibody

Product Images

Western blot analysis of PRRX1 in HeLa cell lysate with PRRX1 antibody at 1 ug/mL.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: PRRX1 antibody was raised against a 19 amino acid peptide near the center of human PRRX1.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: PRRX1 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 27 kDa; Observed: 26 kDa
• Gene Name: phosphatidylinositol 3-kinase catalytic subunit type 3
• Database Link:
  NP_002638
  Entrez Gene 65052 RatEntrez Gene 225326 MouseEntrez Gene 5289 Human
  UniProt ID Q8NEB9
• Background: The paired related homeobox protein 1 (PRRX1) is a paired-type DNA-binding homeodomain that plays an important role as a key switch for neural cell lineage determination and is essential for development (1,2). PRRX1 is expressed in a number of undifferentiated mesenchymal cells in mouse embryos and adults (3). Mice with a disrupted PRRX1 gene show perinatal death with craniofacial and limb malformations (4). Low PRRX1 expression levels were significantly associated with metastasis and poor prognosis of breast and colorectal cancer (5).
• Synonyms: hVps34; VPS34; Vps34

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, Regulation of autophagy