PGC1 alpha (PPARGC1A) Rabbit Polyclonal Antibody

CAT#: TA349142

Rabbit Polyclonal Anti-MALT1 Antibody

Product Images

Western blot analysis of MALT1 in EL4 cell lysate with MALT1 antibody at (A) 1 and (2) ug/mL.

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  Immunohistochemistry of MALT1 in human spleen tissue with MALT1 antibody at 5 ug/mL.

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  Immunofluorescence of MALT1 in human spleen tissue with MALT1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: MALT1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human MALT1.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: MALT1 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 91 kDa; Observed: 96 kDa
• Gene Name: PPARG coactivator 1 alpha
• Database Link:
  NP_037393
  Entrez Gene 19017 MouseEntrez Gene 83516 RatEntrez Gene 10891 Human
  UniProt ID Q9UBK2
• Background: MALT1 was initially identified as a novel gene that was recurrently rearranged in t(11;18)(q21;q21) mucosa-associated lymphoid tissue lymphomas along with the apoptosis inhibitor protein c-IAP2 (1). MALT1, along with the proteins CARMA1 and Bcl10 form an NF-kappaB-activating complex, termed the CBM signalsome, that acts downstream of lymphocyte antigen receptors as well as many other non-lymphoid cell-surface receptors that play a role in multiple cellular functions (2,3). MALT1 has proteolytic activity, and this activity is critical for full NF-kappaB response in T cell activation (4).
• Synonyms: LEM6; PGC-1(alpha); PGC-1alpha; PGC-1v; PGC1; PGC1A; PPARGC1

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Adipocytokine signaling pathway, Huntington's disease, Insulin signaling pathway