CTHRC1 Rabbit Polyclonal Antibody

CAT#: TA349144

Rabbit Polyclonal Anti-CTHRC1 Antibody


USD 484.00

5 Days*

Size
    • 100 ug

Product Images

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Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen CTHRC1 antibody was raised against a 19 amino acid peptide near the amino terminus of human CTHRC1.
Formulation PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification CTHRC1 antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size Predicted: 27 kDa; Observed: 27 kDa
Gene Name collagen triple helix repeat containing 1
Background The Collagen triple helix repeat-containing protein (CTHRC1) is a glycosylated, secreted protein that is transiently expressed in the arterial wall in response to injury where it is thought to contribute to vascular remodeling by inhibiting collagen expression and deposition and promoting cell migration (1). CTHRC1 is highly expressed multiple human cancers, including pancreatic cancer where it plays a significant role in the progression and metastasis of the disease by regulating migration and adhesion of tumors cells (2). CTHRC1 overexpression can also be used as an independent prognostic marker in gastric cancer (3). Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma (4).
Synonyms collagen triple helix repeat containing 1
Reference Data
Protein Families Secreted Protein

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