SNRPN Rabbit Polyclonal Antibody

CAT#: TA349150

Rabbit Polyclonal Anti-SOX4 Antibody

Product Images

Western blot analysis of SOX4 in human testis tissue lysate with SOX4 antibody at 1 ug/mL.

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  Immunohistochemistry of SOX4 in rat testis tissue with SOX4 antibody at 5 ug/mL.

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  Immunofluorescence of SOX4 in rat testis tissue with SOX4 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SOX4 antibody was raised against a 16 amino acid peptide near the amino terminus of human SOX4.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: SOX4 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 52 kDa; Observed: 520 kDa
• Gene Name: small nuclear ribonucleoprotein polypeptide N
• Database Link:
  NP_003088
  Entrez Gene 20646 MouseEntrez Gene 81781 RatEntrez Gene 6638 Human
  UniProt ID P63162
• Background: SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate (1,2). It may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin) (3). SOX4 contains one HMG box DNA-binding domain and may function in the apoptosis pathway leading to cell death. It has also been suggested to play a role in tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development (4,5).
• Synonyms: HCERN3; PWCR; PWS; RT-LI; SM-D; sm-N; SMN; SNRNP-N; SNURF-SNRPN

Reference Data

• Protein Families: Stem cell - Pluripotency