ENT1 (SLC29A1) Rabbit Polyclonal Antibody

CAT#: TA349151

Rabbit Polyclonal Anti-SLC29A1 Antibody

Product Images

Western blot analysis of SLC29A1 in human ovary tissue lysate with SLC29A1 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunohistochemistry of SLC29A1 in human ovary tissue with SLC29A1 antibody at 5 ug/mL.

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  Immunofluorescence of SLC29A1 in human ovary tissue with SLC29A1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SLC29A1 antibody was raised against a 17 amino acid peptide near the center of human SLC29A1.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: SLC29A1 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 50 kDa; Observed: 53 kDa
• Gene Name: solute carrier family 29 member 1 (Augustine blood group)
• Database Link:
  NP_001071642
  Entrez Gene 2030 Human
  UniProt ID Q99808
• Background: SLC29A1 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2). SLC29A1 is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium (3). As a nucleoside transporter, SLC29A1 plays an important role in the uptake of nucleoside-based anti-cancer drugs; polymorphisms of point mutations in the gene encoding this protein may affect the efficacy of these drugs (4).
• Synonyms: ENT1

Reference Data

• Protein Families: Transmembrane