RFX1 Rabbit Polyclonal Antibody

CAT#: TA349171

Rabbit Polyclonal Anti-SRSF3 Antibody

Product Images

Western blot analysis of SRSF3 in K562 cell lysate with SRSF3 antibody at (A) 1 and (B) 2 ug/mL.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SRSF3 antibody was raised against a 19 amino acid peptide near the center of human SRSF3.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: SRSF3 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 18 kDa; Observed: 19 kDa
• Gene Name: regulatory factor X1
• Database Link:
  NP_002909
  Entrez Gene 19724 MouseEntrez Gene 288906 RatEntrez Gene 5989 Human
  UniProt ID P22670
• Background: SRSF3, a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors which constitute part of the spliceosome, may be involved in RNA processing in relation with cellular proliferation and/or maturation (1,2). Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins (3). The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation (3,4).
• Synonyms: EFC; RFX

Reference Data

• Protein Families: Druggable Genome