Ubiquitin D (UBD) Rabbit Polyclonal Antibody

CAT#: TA349179

Rabbit Polyclonal Anti-SLCO1B1 Antibody

Product Images

Western blot analysis of SLCO1B1 in human liver tissue lysate with SLCO1B1 antibody at 1 ug/mL.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SLCO1B1 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human SLCO1B1.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: SLCO1B1 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 76 kDa; Observed: 75 kDa
• Gene Name: ubiquitin D
• Database Link:
  NP_006389
  Entrez Gene 10537 Human
  UniProt ID O15205
• Background: SLCO1B1 is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and may play an important role in the clearance of bile acids and organic anions from the liver (1,2). It contains one Kazal-like domain and belongs to the organo-anion transporter family (2,3). SLCO1B1 is highly expressed in liver and is localized to the basolateral hepatocyte membrane. It is responsible for the hepatic uptake of the liver-specific hydroxymethylglutaryl-CoA reductase inhibitor in mouse, rat and human (3,4).
• Synonyms: FAT10; GABBR1; UBD-3

Reference Data

• Protein Families: Druggable Genome