KIR2DS2 Rabbit Polyclonal Antibody

CAT#: TA349181

Rabbit Polyclonal Anti-KIR2DS2 Antibody


USD 484.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Applications IF, WB
Recommended Dilution WB: 1 - 2 ug/mL
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen KIR2DS2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KIR2DS2. The immunogen is located within the last 50 amino acids of KIR2DS2.
Formulation PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification KIR2DS2 antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size Predicted: 28, 33, 37 kDa; Observed: 34, 42 kDa
Gene Name killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2
Background Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells (1). The KIR proteins are classified by the number of extracellular immunoglobulin domains and by whether they have a long (L) or short (S) cytoplasmic domain (2,3). KIR proteins are thought to play an important role in regulation of the immune response (3). KIR2DS2 downregulates the cytotoxicity of NK cells upon recognition of specific class I major histocompatibility complex (MHC) molecules on target cells and is a receptor on natural killer (NK) cells for HLA-C alleles (3,4).
Synonyms 183ActI; CD158b; CD158J; cl-49; KIR-2DS2; NKAT-5; NKAT5
Reference Data

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